RN Labs Cal-D-Glucarate Powder 50g

Calcium-D-Glucarate is sometimes used by healthcare practitioners to promote optimum liver function, detoxification and reduce excess hormone levels, among other uses.

Key Features

- Calcium-D-glucarate is the calcium salt of D-glucaric acid, a substance produced naturally in small amounts by mammals, including humans.
- Calcium-D-glucarate demonstrates detoxification properties, supporting the excretion of potentially toxic compounds.
- Phase II detoxification facilitates excretion of chemical carcinogens, steroid hormones, and other lipid-soluble toxins via conjugation with glucuronic acid in the liver (glucuronidation), allowing water soluble excretion into the intestinal lumen.
- Calcium-D-glucarate has been shown to inhibit beta-glucuronidase, an enzyme produced by colonic microflora, capable of deconjugating bound toxins, making it possible for them to be reabsorbed rather than excreted.
- Elevated beta-glucuronidase activity has been associated with an increased risk for various cancers, particularly hormone- dependent cancers such as breast, prostate, and colon cancers (potentially due to accumulation of excess hormones and toxins).
- Calcium-D-glucarate’s inhibition of betaglucuronidase activity allows the body to successfully excrete excess hormones (such as oestrogens) before they can be reabsorbed, reactivated and recirculated within the body.